Pharmaceutical

who advances drug delivery? we do.

Our pharmaceutical team prides itself on advancing drug delivery with sophisticated science-based solutions. Our global centers of excellence contain the latest equipment and our research scientists and formulators are ready to work with you from concept to commercialization.

always solving™ for formulators, manufacturers and patients
We meet formulators' needs by providing an unparalleled range of excipients and technologies, as well as longstanding polymer expertise and technical support for oral solids, liquids, topical and parenteral dosage forms. Our solutions include: increasing API solubility, controlled release, disintegrants, film coatings and tablet binders. Our full line of products combined with our global research and development capabilities can help deliver your drugs when and where they're needed resulting in better outcomes for patients and pharmaceutical companies alike.

With its significant history in pharmaceuticals and one of the widest available range of products for oral solid-dosage forms, Ashland has a solid foundation to help find excipient and formulation solutions for you. Our global manufacturing sites, that operate in accordance with cGMP standards, provide consistently high quality products regardless of origin. As a full-service resource, Ashland can help you bind, coat, dissolve and deliver solutions that can yield better patient outcomes.

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an overview of our pharmaceutical focus

 

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  • oral solid dosage form

    prescriptions for successful solutions

    While an apple a day keeps the doctor away (and the teacher happy) there comes a time in almost everyone's life when medication is needed. Our knowledge of the structure function of polymers, combined with our extensive product line can help you bind, coat, dissolve, and effectively deliver complex drug molecules where and when they're needed - making medication easier to swallow for your patients. 

    We pride ourselves on our ability to develop solutions for effective and efficient solutions to deliver today's complex drug molecules where and when they are needed. Our centers of excellence and manufacturing sites operate in accordance with cGMP standards. Our various chemistries and technologies are supported by a global team of research and development scientists. Ashland stands ready collaborate with you on new solutions to help take you from concept to commercialization.  Our solutions include:

    • Increasing the solubility of active pharmaceutical ingredients with low or no solubility
    • Designing modified-release products to meet targeted release profiles
    • Reducing tablet size while maintaining active pharmaceutical ingredient load
    • Improving disintegration time of orally disintegrating tablets
    • Understanding implications of continuous manufacturing technology for oral dosage production

    Ongoing research provides a foundation for advanced technical solutions to address these and future formulation and manufacturing challenges. Ashland provides formulators with industry-changing technologies and unique opportunities for research and development collaboration.

     

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  • oral liquid dosage form

    helping the medicine go down

    Effective drug delivery in liquid form poses some unique challenges with rheology, texture, consistency and stability at the top of the list. Ashland's promise - always solving™ - inspires our goal of willing to work with you to find new sophisticated solutions to advance drug delivery. With our extensive polymer portfolio, R&D capabilities and testing facilities combined with your complex drug molecues, we can yield solutions that both deliver and improve the bioavailability of needed medication.

    Targeted rheology, texture and stabilization in oral-liquid dosage forms play vital roles in delivery of the pharmaceutical components. The water binding and viscosity modification capacities of many of Ashland’s polymers thicken and suspend in liquids, gels, syrups and semi-solid dosage forms for improved patient satisfaction and shelf life of products. 

     

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  • parenteral dosage form

    solutions that are more than skin deep

    Bioresorbable polymers have been commercialized for more than 50 years, however, until now, no manufacturer has offered a single source of three key excipients used to formulate these revolutionary drug delivery systems that are designed to improve patients’ lives.

    With the addition of Viatel™ bioresorbable polymers, Ashland provides a comprehensive line of products for parenteral, controlled release drug delivery. Complementary excipients include Aqualon™ CMC PH BET sodium carboxymethyl cellulose, a suspending agent for two-component systems; and Pharmasolve™ n-methyl-2-pyrrolidone, a versatile solubilizer for one-component systems.

    Parenteral formulations present unique challenges to formulators. Ashland has products that can help address these challenges.

     

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learn more about our solutions

  • bioavailability enhancement

    Poorly water-soluble active pharmaceutical ingredients (APIs) pose ongoing development challenges. Common techniques to improve API solubility, such as salt formation and particle-size reduction, do not always result in the solubility levels required to achieve desired bioavailability.

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  • disintegrants

    Effective tablet disintegration is necessary for active pharmaceutical ingredient (API) dissolution and release. And at Ashland, we know that this is often a challenge that needs solving, and we're eager help.

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  • film coatings

    Your tablet film coatings are the outward expression of your product’s quality. That’s why our team is always solving – to provide you with effective, high-quality coatings that perform in the manner you require, while also delivering the right color and aesthetic.

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  • controlled release

    Ashland offers sophisticated solutions to address a wide variety of controlled release delivery models. The team of passionate, tenacious solvers at Ashland can deliver controlled release solutions that can improve the efficacy of your drug molecules.

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  • tablet binders

    Pharmaceutical companies want smooth, round, uniform tablets for their products delivered as oral solid dosage. The pharmaceutical solvers at Ashland stand ready to help identify and select the best binder for your situation.

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  • EXCiPACT certifications

    With six manufacturing facilities already certified by EXCiPACT, Ashland is well on its way to have all pharmaceutical excipient facilities certified by the end of 2017. Ashland continues its quest for high quality, which in turn, simplifies and streamlines your sourcing options.

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