tablet binding

Choosing the right binder is critical to maintaining the integrity of the tablet. A formulator must know if the desired release profile is immediate or modified. Release profiles for a given active pharmaceutical ingredient (API) can be controlled through selection of binder chemistry and molecular weight. With the exceptional range of binders produced by Ashland, you can be sure of finding the right one for your formulation. Ashland produces binders for wet granulation, dry granulation, direct compression and roller compaction, as well as hot-melt extrusion.

Klucel™ hydroxypropylcellulose (HPC) is our most versatile binder (different grades can be used in wet granulation, dry granulation, roller compaction or hot-melt extrusion) and is the first choice for many formulators. With the variety of functional polymers available in the Ashland portfolio, there is a high likelihood that one of our products will deliver the performance you need. We offer tablet binders for dry and wet granulation, direct compression, roller compaction, and hot-melt extrusion to fit with your manufacturing processes and needs. 

Ashland’s extensive history in, and research on, excipients  is combined with an unsurpassed understanding of the physics of tablet binding. Although many companies have knowledge, Ashland’s ability to apply this extensive knowledge to deliver practical usable solutions that, not just offer differentiation, but benefits you, creating a profitable difference.  Select a partner that has the knowledge, expertise and experience to identify an appropriate binder.  Reducing the risk of using the wrong binder saves time, money, and reputation, and mitigates ineffective drug delivery. The pharmaceutical solvers at Ashland stand ready to help identify and select the best binder for your situation. 

 All Ashland binders are produced under strict cGMP standards to ensure the quality and consistency of the products.


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