Ashland offers a broad range of cyclodextrin products
unique solutions for pharmaceutical formulations
Ashland offers and supports a robust range of native cyclodextrins and derivatives to help you achieve the desired benefits in final drug formulation.
key features and benefits
- increase solubility and enhance bioavailability in oral, parenteral, ophthalmic, topical, and liquid-dosage forms
- provide low bioburden and endotoxin grades that meet defined limits for use in parenteral and ophthalmic dosage forms
- offer grades with differing degrees of substitution to maximize performance
- provide taste masking
Ashland provides a range of HPBCD and HPGCD products, including:
CAVASOL® cyclodextrin derivatives
The molecular structure of cyclodextrins creates a bucket-like cavity that can function to complex with molecules or functional groups on molecules. The substitution of hydroxyl groups on native cyclodextrins to make hydroxypropyl-ß- cyclodextrins (HPBCD) significantly enhances their solubility and makes them more suitable for drug solubilization.
vailable formulations include:
cavitron™ cyclodextrin derivatives
The cavitron™ hydroxypropyl-β-cyclodextrin grades are differentiated by degree of substitution. These grades are manufactured to meet defined bioburden and endotoxin limits intended for use in the manufacture of parenteral preparations and other applications requiring high purity, while the CAVASOL® cyclodextrin grades are suitable for oral applications.
available formulations include:
- cavitron™ w7 hp5 pharma cyclodextrin
- cavitron™ w7 hp7 pharma cyclodextrin
- cavitron™ w7 hp7 API pharma cyclodextrin
CAVAMAX® native cyclodextrins
CAVAMAX® cyclodextrins have the unique ability to act as molecular containers by entrapping guest molecules in their internal cavities. The resulting inclusion complexes are used in a number of applications in pharmaceutical formulations.
available formulations include:
- CAVAMAX® w6 pharma α-cyclodextrin
- CAVAMAX® w7 pharma β-cyclodextrin
- CAVAMAX® w8 pharma γ-cyclodextrin
CAVAMAX® and CAVASOL® are manufactured by Wacker Chemie for pharmaceutical applications around the world. The alliance with Wacker combines Wacker’s cyclodextrin manufacturing expertise with Ashland’s technical sales and customer service capabilities to provide solutions for formulating pharmaceutical products.
Contact us today to learn how Ashland’s cyclodextrin products can offer you and unique solution for your pharmaceutical formulations.
CAVAMAX® and CAVASOL® are registered trademarks of Wacker Chemie AG.
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