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related published innovation papers
| title/description | authors | related technologies |
|---|---|---|
| The aim of this study was to develop a hydrophilic oral controlled release system (CRS) using the amorphous form of gliclazide, a BCS class II compound, listed on the WHO list of essential medicines. For this purpose, spray-dried dispersions (SDDs) of gliclazide were produced using various grades of hydroxypropyl methylcellulose acetate succinate (HPMCAS) or copovidone as carrier under fully automated conditions | Lu, Zheng, Yonglai Yang, Rae-Ann Covington, Yunxia Vivian Bi, Thomas Dürig, and Reza Fassihi | polysaccharides, acetylenics |
| Cocrystals, Coamorphous Phases and Coordination Complexes of γ-and ε-Lactams | Hall, Amy V., Luke I. Chambers, Osama M. Musa, and Jonathan W. Steed | acetylenics |
| Development of carvedilol-cyclodextrin inclusion complexes using fluid-bed granulation: a novel solid-state complexation alternative with technological advantages | Ellen C P Alonso, Karina Riccomini, Luis Antônio D Silva, Daniela Galter, Eliana M Lima, Thomas Durig, Stephania F Taveira, Felipe Terra Martins, Marcílio S S Cunha-Filho, Ricardo N Marreto | polysaccharide |
| The preparation of graft copolymers of cellulose and cellulose derivatives using ATRP under homogeneous reaction conditions | Joubert, F., Musa, O. M., Hodgson, D. R. W., & Cameron | polysaccharide |
| Cyclodextrin-Efavirenz Complexes Investigated by Solid State and Solubility Studies | Braga, Susana S., Karyna Lysenko, Firas El-Saleh, and Filipe A.A. Paz | polysaccharide |
| Radiochromic Film as a Tool for Development of Sun Protection | Duev, A., Dueva-Koganov, O. V., Shih, S., Crohn, R., Aydin, R., & Menchon, M. | acetylenics |
| Is It Possible to Publish a Calibration Function for Radiochromic Film? | Chan, Maria F., Lewis D., Xiang Yu | acetylenics |
| Inclusion Compound of Efavirenz and γ-Cyclodextrin: Solid State Studies and Effect on Solubility | Braga, S. S., El-Saleh, F., Lysenko, K., & Paz, F. A. A. | acetylenics |
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This work aimed at obtaining an optimized itraconazole (ITZ) solid oral formulation in terms of palatability and dissolution rate by combining different polymers using hot melt extrusion (HME), according to a simplex centroid mixture design. For this, the polymers Plasdone® (poly(1-vinylpyrrolidone-co-vinyl acetate) [PVP/VA]), Klucel® ELF (2-hydroxypropyl ether cellulose [HPC]), and Soluplus® (SOL, polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol) were processed using a laboratory HME equipment operating without recirculation at constant temperature. |
Malaquias, L. F. B., Schulte, H. L., Chaker, J. A., Karan, K., Durig, T., Marreto, R. N., Gratieri, T., Gelfuso, G. M., & Cunha-Filho | polysaccharides, acetylenics |
| Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms | Mogen AB, Chen F, Ahn SJ, Burne RA, Wang D, et al. | functional molecules |
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To enhance oral bioavailability and antioxidant potential of resveratrol by fabricating the resveratrol encapsulated oral eudragit® E100 based polymeric nano-delivery system. |
Hasija, R., S. Chaurasia, and Swati Gupta | acetylenics |
| Resveratrol-Loaded Poly(d,l-Lactide-Co-Glycolide) Microspheres Integrated in a Hyaluronic Acid Injectable Hydrogel for Cartilage Regeneration | Wang, X., Li, X., Duffy, P., McMahon, S., Wang, X., Lyu, J., Xu, Q., A, S., Chen, N.N., Bi, V., Dürig, T. and Wang, W. | polyesters |
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The formulations without Eudragit E PO (F6) and with Eudragit E PO (F7) filaments exhibited the desired hardness with a “k” value of 48.30 ± 3.52 and 45.47 ± 3.51 g/mm3 (n = 10), respectively, and were successfully printed. |
Wang, H., Dumpa, N., Bandari, S. Durig, H | acetylenics |
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Binary, ternary and quaternary dispersions containing GF, enteric polymer (Eudragit L100-55 or AQOAT-LF) and/or vinyl pyrrolidone-based polymer (Plasdone K-12 povidone or S-630 copovidone) were processed by HME. |
Ryan C Bennett, Justin M Keen, Yunxia (Vivian) Bi, Stuart Porter, Thomas Dürig, James W McGinity | acetylenics |
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