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Benecel™ methylcellulose and hypromellose

Benecel methylcellulose and hypromellose (hydroxypropylmethylcellulose or HPMC) are two of the most versatile excipients. High-viscosity grades are widely used in hydrophilic matrix controlled-release systems. Low-viscosity grades are the primary film former in tablet coatings and vegetarian capsules, and are a common wet granulation binder; a widely used wet granulation binder 

Benecel products labeled with the PH suffix are compliant with the monograph requirements of the current editions of the National Formulary, the European Pharmacopoeia and the Japanese Pharmacopoeia.

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Applications
Description
Benefits
Coatings
Low-viscosity Benecel HPMC is a widely used film former for tablet coatings.

• Low viscosity with good film strength
• Compatible with pigments, plasticizers, and other coating additives

Immediate Release Binders
Low-viscosity grades are used in wet granulation.

• Good binding efficiency
• Low viscosity allows for high concentrations

Liquid and Semi-Solid Rheology Control
Benecel can be used for thickening suspensions and syrups.

• Thickens in cold water
• Suspends particulates

Modified Release Binders
High-viscosity grades are a common gel-forming polymer for hydrophilix matrix tablets.
• Strong gel formation

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Product Literature (publicly available)
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Safety Data Sheets

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Additional InformationNeed more information about this product?

USP Substitution Type Benecel HPMC Grade Nominal USP Viscosity, cps
Methylcellulose A15 PHARM 1500
  A4M PHARM 4000
2910 E3 PHARM 3
  E5 PHARM 5
  E6 PHARM 6
  E15 PHARM 15
  E50 PHARM 50
  E4M PHARM* 3600
  E10M PHARM* 10000
2208 K100LV PHARM* 100
  K250 PH PRM*  
  K750 PH PRM*  
  K1500 PH PHARM*  
  K4M PHARM* 3600
  K15M PHARM* 18000
  K35M PHARM* 35000
  K100M PHARM* 100000
  K200M PHARM* 200000

 *Fine particle size controlled release (CR) grades also available.

Market InformationWant to know more about where our products are used?

Markets
Applications
Product Types or Functions
Pharmaceutical
Coatings, Immediate Release Binders, Liquid and Semi-Solid Rheology Control, Modified Release Binders
Binder, Coating Polymer, Rheology Modifier

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