Pharmasolve™ N-methyl-2-pyrrolidone
Pharmasolve N-methyl-2-pyrrolidone (NMP) is a water-miscible polar aprotic solvent with high interfacial activity. It is used as a drug solubilizer and penetration enhancer in human topical dosage forms, and for the same purposes in parenteral and topical veterinary products.
The regulatory compliance information for all Ashland products varies by product family and grade. For specific data about the grade you are interested in please refer to our Excipient Information Package and the Certificate of Analysis (COA).
Explore other products: Excipients, Specialty Ingredients
Product Availability
- Asia Pacific
- Europe, Middle East, Africa, India
- Latin America and South America
- North America
Application InformationWant to know more about how our products are used?
Drug solubilizer and penetration enhancer in topical dosage forms. Enhanced solubility is seen in select drugs when Pharmasolve NMP is included in the formulation, because of the polar nature of the molecule.
• In topical applications, improves solubility of a wide range of water-insoluble drug actives
Drug solubilizer and penetration enhancer in parenteral and topical dosage forms. Enhanced solubility is seen in select drugs when Pharmasolve NMP is included in the formulation, because of the polar nature of the molecule.
• Enhanced solubility of select drugs
• Enhanced permeability of drugs through the skin
• Increased bioavailability of select drugs
• Inherently stable material
• Resistant to hydrolysis
• Proven in antibiotics and sulfa drugs, steroids and anti-inflammatory compounds
Document LibraryInformation available to download for this product.
- Existing Customer?
- Log in to access
- Prospective Customer?
- Request a Safety Data Sheet