Aquarius™ Control film coating systems
The Aquarius Control film coating systems consist of two types of coatings. Aquarius Control ENA film coating systems are delayed-release (enteric) coatings that are designed to protect active pharmaceutical ingredients (APIs) that degrade in gastric fluid, or to prevent the release of APIs that may irritate the gastric mucosa. Aquarius Control SRX film coating systems are sustained-release coatings for APIs that are most effective when released over time.
These film coating systems have predictable and controllable release retardation; are custom formulated based on drug solubility and desired release profile; do not require a coalescence step and have stable dissolution profiles over a wide pH range. Aquarius Control film coating systems are durable, coherent coatings, in which film formation occurs via solvent evaporation – not latex coalescence – and film robustness is related to the use of a high-molecular weight polymer.
Aquarius Control SRX film coating systems are fully formulated, solvent-dispersible ethylcellulose (EC) coatings for multiparticulates, potentially modified with hydroxypropylcellulose (HPC) as a pore former. They are available in several different porosities that can be matched to drug solubility and/or desired release profile. A key benefit of Aquarius Control SRX film coating systems is that they do not require curing after coating.
The release profiles of tablets enteric coated with Aquarius Control ENA film coating systems are remarkably stable over periods of up to 12 months, even under accelerated stability testing.
The regulatory compliance information for all Ashland products varies by product family and grade. For specific data about the grade you are interested in please refer to our Excipient Information Package and the Certificate of Analysis (COA).
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Product Availability
- Asia Pacific
- Europe, Middle East, Africa, India
- Latin America and South America
- North America
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Aquarius film coating systems are high-solids coatings for pharmaceutical and nutritional tablets. Specialty grades are available for modified release and barrier properties.
• Optimum balance of film strength, flexibility and adhesion
• Available in clear, white and color formulations
• SRX grades provide customized release profiles for multiparticulate systems
• ENA grades are highly effective enteric coatings
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- Technical Information
- Aquarius™ Coating Systems Overview and Performance
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